A dual functional AEE fluorogen as a mitochondrial-specific bioprobe and an effective photosensitizer for photodynamic therapy.
نویسندگان
چکیده
We report a dual functional aggregation-enhanced emission (AEE) molecule, TPE-IQ, which could target and illuminate mitochondria in both live and fixed cells with superb selectivity and high signal-to-noise ratio. More intriguingly, TPE-IQ can serve as a photosensitizer to generate reactive oxygen species (ROS) in the mitochondria region to induce cell apoptosis.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 92 شماره
صفحات -
تاریخ انتشار 2014